ANP 1107 Lecture Notes - Lecture 21: Renal Function, Aldosterone, Glucocorticoid
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Germinal period conception to 2 weeks, if e(cid:373)b(cid:396)(cid:455)o does(cid:374)"t de(cid:448)elop, it (cid:449)ill be shed b(cid:455) (cid:373)othe(cid:396)"s (cid:374)o(cid:396)(cid:373)al pe(cid:396)iod; Embryonic period 3-8 weeks, most sensitive to prenatal deformities, mother may not even know they are pregnant (be careful to what she is exposing her baby to); fetal period 9 weeks to term. Placentation maternal and fetal blood supplies are not in direct contact nutrients, gases, wastes, diffuse through trophoblast, mesenchyme, fetal capillary endothelium normal term placenta is ~500g, measures 15-20cm diameter, 2-3 cm thick; umbilical cord is usually 50- Human chorionic gonadotropin (hcg) present in maternal serum by 8th day after fertilization, levels peak by 60- Estrogens initially come from corpus luteum, function gradually assumed by placenta placenta converts circulating androgens (fetal and maternal adrenal glands) to estrogen initially estrone and estradiol-17-beta, then estriol; maintains uterine endometrium, contributes to breast development. Intestines slow down motility and can have problems with constipation.