APA 2120 Lecture Notes - Lecture 8: Substantia Nigra, Basal Ganglia, Intention Tremor

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Dysmetria: refers to a lack of coordination of movement typiied by the undershoot or overshoot of intended position with the hand, arm, leg, or eye. Cerebellar ataxia: can occur as a result of many disease and presents with symptoms of an inability to coordinate balance, gait, extremity and eye movements. Near the base of the brain, is a small area called the substantia nigra which contains cells that produce dopamine. Parkinson"s disease: allows desired movement to happens while inhibiting movements, degeneration of substantia nigra, pd is a neurological disorder. Afects more than 1m americans (. 4% of pop) (underreported) Afects men slightly more than women: pd associated with malfunctioning basal ganglia. Symptoms of pd: rigidity-increased stifness and resistance to joint movements, tremor, balance deicits leads to falling, walking problems (shuling, freezing, bradykinesia slow movement (initiation and production) L-dopa is converted to dopamine by the body and relieves symptoms: surgery: On" phase 30 minutes after medication, substantial changes in gait.

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