BCH 2333 Lecture Notes - Lecture 2: Covalent Bond, Relative Permittivity, Benzene

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The covalent bonds that we are really interested in include, esters, thioesters, and amides. These bonds are reversible, thus allowing us to control them. However everything can"t be covalent because they are harder to break, take up a lot of energy. Non-covalent bonds are weak individually making them easier to break. In a cluster they are stronger but individually they are easy to break apart. Example: dna has both covalent and non-covalent interactions. The intra-chain bonding is covalent (phosphor diester bonds). Thus it can be zipped and unzipped at a very low cost. The intra chain is covalent and the inter chain is non-covalent. Just like dna base pairing many other interactions are non-covalent in biochemistry. It allows reversibility at a very low cost. The interactions are arranged in three categories: i) Can be between a full ion and a dipole. Can be between dipole dipole (two things with partial charges)

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