BIO 1130 Lecture Notes - Lecture 4: Red Blood Cell, Allele Frequency, Sickle-Cell Disease

• School: University of Ottawa
• Department: Biology
• Course: BIO 1130
• Professor: Jon Houseman

Document Summary

Synthetic (modern) theory of evolution: huxley i(cid:374) the ea(cid:396)l(cid:455) (cid:1005)9(cid:1004)(cid:1004)"s, linking population genetics, natural selection and mendelian genetics, believes that genes are in the population as alleles and there is a mixture of alleles in population. If allelic frequency is followed, leads to natural selection: population genetics and natural selection based on mendelian genetics. Evolutionary changes that result from changes in allele frequencies in a population, or in chromosome structure or numbers due to mutation and recombination. Basically: allelic frequency changes in a population. Mendel figured out that each organism has to have two copies of each trait in order to have such high allelic frequency. Genotype the alleles of the organism. Homozygous has two of the same alleles. Figured out the mathematics of allele frequency. Gives us the major forms that we associate with population biology or measuring microevolution. In normal complete dominance, ratio of offspring is 3:1 (3 dominant, one recessive)