BIO 1140 Lecture Notes - Mitogen-Activated Protein Kinase Kinase, Protein Kinase B, Protein Kinase
22 Dec 2012
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Document Summary
Involves a direct cytoplasmic link between the cells for small molecules to pass through: contact. Involve membrane proteins that recognize other elements of the cell matrix and bind to them. With respect to cadherins, the 2 cells have to recognize each other because of the cadherins. What occurs in the junctions (i. e. : adherins junctions / focal junctions) affects what is going on in the cell. E. g. : for cell crawling, focal adhesions must be made and then let go again. What goes on in the cell determines what happens with the focal adhesions: chemical messengers. Can be produced by different kinds of cells: hormones. Chemical messengers that are synthesized by cells (i. e. : specialized cells called endocrine cells) Carried to a distant target cell (in the blood or extracellular fluid) Important in large, multicellular organisms where you want to integrate activities of different parts of the organism that are distant from each other: paracrine messengers.
