BIO 1140 Lecture Notes - Lecture 4: Macrophage, Glycocalyx, Glycolipid

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January 27th
Cell Biology- Topic 4
-Learning objectives are guidelines for the exam
-Merae potetial o’t e o ea
Question 1
True
Towards plus end does go to periphery, toward plasma membrane
There are 2 motor proteins that travel in different directions
This is an axon, propose a way this portion of a cell can grow to reach a target
(eg.muscle). Describe the structural elements involved and the steps required.
My guess: F-actin network and the dynamic microtubule will be expanded on by
the motor proteins, and this growth will give the axon shaft room to expand and
reach its target
Answer: First thing that needs to happen is to receive a signal or a message, that
will trigger it to grow. Inside the cell, microtubules will have to extend. To do
this, tubulin diamers will have to attach, alpha end to beta end. Tubulin will need
to be available to do this. Part of this tubulin dimer is the positive end, which will
need GTP at the extremity. To get to this end, we will use mottr protein kinesin.
Then, to build the microfilaments, actin subunits are used. Microfilaments,
eause the are’t hollo like irotuules ad gro staggered, hae the
ability to branch out. As this is growing, it is pushing on the cytoplasm and
moving it out (although not enough to move the whole way). We are already
shuttling vesicles taking waste out of the cell, and when proteins are prodced,
more vesicles are formed with plasma membrane.Once they fuse to the plasma
membrane, more and more additionl plasma membrane is brought with it. This
becomes the source of phospholipids
***Find better, organized answer
Slide 5
Membrane are used to attach cells together, to have specialized structures that
allow communication between cells
Ex. Gap junctions, plasmodesmatae
Where structures that control what goes in and out of the cell are found
The composition of membrane affects its selective permeability
Features in membrane that allows cells to receive signals
Slide 6
All membrane is not the same
On a neuron, membranes can be different on different sections of that structur
A double layer on mitochondria adds permeability
Doube layer of phospholipids with an extra specialized layer(ex.glycocalx)
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Document Summary

Me(cid:373)(cid:271)ra(cid:374)e pote(cid:374)tial (cid:449)o(cid:374)"t (cid:271)e o(cid:374) e(cid:454)a(cid:373: question 1. Towards plus end does go to periphery, toward plasma membrane. There are 2 motor proteins that travel in different directions: this is an axon, propose a way this portion of a cell can grow to reach a target (eg. muscle). Describe the structural elements involved and the steps required. My guess: f-actin network and the dynamic microtubule will be expanded on by the motor proteins, and this growth will give the axon shaft room to expand and reach its target. Answer: first thing that needs to happen is to receive a signal or a message, that will trigger it to grow. Inside the cell, microtubules will have to extend. To do this, tubulin diamers will have to attach, alpha end to beta end. Tubulin will need to be available to do this. Part of this tubulin dimer is the positive end, which will need gtp at the extremity.

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