BIO 2133 Lecture 10: Lecture 10

• School: University of Ottawa
• Department: Biology
• Course: BIO 2133
• Professor: Colin Montpetit

Document Summary

Based on the pedigree, which inheritance pattern can be ruled out: autosomal dominant, autosomal recessive, x-linked dominant, x-linked recessive, none of these. Mendelian crosses: establish true-breeding lines each of which exhibit clear character differences, make crosses between each pair of lines, make crosses between the progeny. Recessive: summary, pedigrees show transmission of specific traits in family trees, helpful in inferring mode of inheritance and in gene mapping. Determine the mode of inheritance presented in this pedigree: autosomal dominant, autosomal recessive, cannot be determine. Product rule: the probability of two or more independent events all occurring = the product of the individual probabilities. Sum rule: the probability of two or more mutually exclusive outcomes = sum of the individual probabilities. Look up the p value in a x2 table: p is the probability that the null hypothesis is true, and a deviation this large is due to chance.