BIO 3102 Lecture Notes - Lecture 1: Tumor Suppressor Gene, Phasmatodea, Gene Duplication
29 Aug 2016
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Study of evolution of macromolecules: changes in dna and protein and their impact. Evolutionary change involved genetic change: genotype leads to phenotype. 2. rrnas and trnas are uses as a fundamental system (triplet code) More cell divisions = more chances for mutation: elephants longer lives low cancer rate, possible due to many copies of p53 tumor suppressor gene, their smaller short lived ancestors only had one pair of p53 genes. Tree of life: brown blob: primitive eukaryote, tips extant organisms (animals, plants, fungi, star protists, archea triangle, bacteria circle (connections to plants and eukaryote through chloroplasts and mitochondria, endosymbiotic origins of chloroplasts from cyanobacteria. Web of life : far more complex scenario than darwin could have imagined, many microbes swap genes back and forth, or engage in gene duplication, recombination, gene loss or gene transfers . Evolutionary information from dna sequences: gene, sequence of dna (or rna) that is essential for a specific function, 1.
