BCH 2333 Lecture Notes - Lecture 22: Hydrophile, Antibody, Small Molecule
16 Dec 2017
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Document Summary
Molecular imaging is a way to monitor and record the spatiotemporal distribution of molecular processes for biochemical, biological, diagnostic, or therapeutic applications. Anatomical: 2d image at one time point (ex. Functional: shows movement, shows us what is going on at a macroscopic level - doesn"t tell us anything about the molecules (ex. echo) Molecular: start to see subcellular mechanisms, can see what"s going on in the cells biochemically, can non- invasively see what"s going on biochemically (ex. Pet, fmri - shows where the brain is using glucose) Molecular imaging can also be though of as a non-invasive 3d biopsy. Biopsy: take a section of the tissue of interest, stain it, and then look at it under the microscope: invasive, painful. Trying to get imaging to give biopsy level information over the entire organism, not just one area. Good for cancer: ex. can look at the whole tumour without needing to biopsy multiple areas.
