BPS 1101 Lecture Notes - Lecture 2: Aspirin Poisoning, Salicylic Acid, Sammy Cahn
22 Jan 2018
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We can now do surgical procedures we couldn"t before. We can now control quality of life. You don"t need a prescription, but you need to ask. Aspirin- one of the world"s most popular drugs. Sumerians used willow leaves for pain (2200 bc) Knowledge of herbs lost in dark ages. Claims he tasted the willow bark and it had a bitter taste. People who live near swamps get malaria. Chemical structures represent the shape and function of molecules. A little salicin from a lot of bark. Occurs in meadowsweet flowers (very small amounts) Coal tar was a waste product in 1800s. Dye companies specialized in coal tar chemistry. Salicylic acid made and sold by dye companies. Salicylic acid was a drug with problems. Developed for the first time, an artificial drug. More useful name to help search for/compare products. Ringing in the ears- more than 10 tablets. One aspirin tablet every 2 days for 5 years:
