BPS 1101 Lecture 9: Lecture 9 -Vaccines

• School: University of Ottawa
• Department: Biopharmaceutical sciences
• Course: BPS 1101
• Professor: William Ogilvie

Document Summary

Vaccines: when you get sick you develop immunity to the sickness, body has built in immunity. Increased age leads to an increase in immunity. What vaccines are doing: vaccines create a (cid:862)fake ill(cid:374)ess(cid:863, generate immunity without the sickness. What they do: creates a sick illness, body will generate a long term memory bcs of exposure to the virus, generate immunity without sickness. Immune system uses many weapons: poisons, defensins, complement, antibodies. Immobilize invaders: selectively destroy invaders, macrophages, specialized cells to eat foreign cell, specialized cells to kill infected cells. Immediate non-specific response: all cells are targeted. Immediate maximum response: cold symptoms caused by the innate immune system, responds to damage, release cytokines inflammation, redness, swelling or recruit leukocytes to destroy microbes, leukocytes destroy the invaders. Inflammation gives easier access for the immune cells: gives easier access to wbc to be where they need to be. Adaptive immunity: specific response (selective but slow)