BPS 1101 Lecture Notes - Lecture 3: History Of Lysergic Acid Diethylamide, Sumatriptan, Prodrome

• School: University of Ottawa
• Department: Biopharmaceutical sciences
• Course: BPS 1101
• Professor: William Ogilvie

Document Summary

Once believed headaches were caused by demons: would cut open head to relieve headaches. Only 30% survived procedure: known as trepanaion. Brain does not feel pain, the issue around your skull does. Muscular headaches: muscle band around skull becomes tense, causing headaches. Stress induced: treated with ibuprofen, asa, naproxen or acetaminophen. Pain is caused by vasodilaion (blood vessels expand and squish issue) Toxic headaches (eaing something your body does not like/hangovers: asians likely to get worse hangovers. It does not: cafeine can cause headaches if you ingest it then stop, can be treated with asa, ibuprofen, naproxen. Only 18% women & 6% of men get them ever: 2 phases of a migraine. Diameter of blood vessel shrinks down a lot. Creates migraine pain: migraines iniiated by a trigger (stress, tension, food, pregnancy, smells, etc. , 4 stages of progression of a migraine: Ergot: grew on rye bread in the past.