BPS 1101 Lecture Notes - Lecture 10: Peanut Allergy, Contact Dermatitis, Allergic Rhinitis

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Adverse reactions to harmless materials: immune system tricked into overreacting. Requires prior exposure: immune system responds to something. Epitopes of molecules from pathogens: immune system remember that material. Memory cells build up: subsequent exposure produces reaction. Can contact dermatitis from irritants: hand washing makes it worse, common with industrial powders. Exposure to large amounts of powder: stuff like flower, sugar, and baking soda can cause this problem. Dose makes the poison: the amounts are what is important, when you work with it all day every day, your exposure increases. Contact dermatitis from immune reaction (ex. poison ivy/poison oak: immune reactions at the site of contact cause blistering and rashes, urushiol produces the reaction. Latex from rubber tree sap: can develop if the work with if a lot in industry, found in gloves and condoms. Nickel: alloys are common (coins, belts, keys, zippers, etc. ) Added to other substances to make the metal harder: many piercings made of stainless steel.

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