BPS 2110 Lecture Notes - Lecture 16: Immunogenicity, Alipogene Tiparvovec, Hemoglobin
7 Nov 2017
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Document Summary
Explain the details of the original technology developed by medicago for quick and mass production of antibodies. List and brie y explain the differences between biologics and small-molecule drugs. Explain the different steps and intermolecular interactions involved in the formation of an antigen-antibody complex. Biologics are becoming more and more popular - they"re here to stay. Sales have almost doubled between 2006 and 2012. Regulated by the centre for vaccine evaluation (cve) Radiopharmaceutical"s, hormones, cytokines, enzymes, gene therapies, monoclonal antibodies, allergenic extracts. Regulated by the centre for evaluation of radiopharmaceuticals and biotherapeutics (cerb) Radiopharmaceuticals: radio labelled drugs used for visualization in imaging. Blood and blood components, coagulation factors, immune globulins and other plasm derivatives and there recombinant analogues, cells and cell-based medicines, tissues and organs, xenografts, semen for assisted contraception. Regulated by the centre for blood and tissues evaluation (cbte) Complexity: biomolecules are signi cantly larger than conventional drugs and they are stereospeci c.
