CHM 2123 Lecture Notes - Lecture 3: Nucleophile, Molar Mass, Leaving Group

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In an ideal situation, a reaction will yield only one product, which rarely ever happens. This leads to two products: minor and major, which is the one that scientists are interested in. These products are formed via two mechanisms, elimination or substitution, which are always in competition with each other. The favourability of one mechanism over another is determined by the conditions in which the reaction takes place, the reactants used, the strength of the nucleophiles and electrophiles, and the solvent. In order to determine the overall yield of the molecule of interest, a simple yield calculation is not enough. The conversion determines the percentage of how much product was formed. The selectivity determines the percentage of how much one product was favoured over another. The purpose of this experiment was to show how changing the reaction conditions and electrophiles can have an effect on which reaction, of the two studied,

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