HSS 4102 Lecture Notes - Lecture 10: Glyphosate, Coeliac Disease, Cytochrome P450

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It is an important compound involved in development but can disrupt it if it is in the wrong amount or at the wrong times. Ra is important for the formation of the anterior-posterior axis in mammals and for heart and jaw formation. Of 59 pregnant women exposed to accutane. If present in high amounts, cells usually not exposed to it will respond to it. Isotretinoin (13-cis-retinoic acid) accutane was used for treatment of acne in the early 80"s: 26 had no noticeable anomalies, 12 aborted spontaneously, 21 were born with anomalies. Anomalies included absent or defective ears, absent or small jaws, cleft palate, aortic arch abnormalities, thymic deficiencies, and cns abnormalities. Glyphosate and autism: data shows correlations between increase in neurological diseases and gmo"s. Glyphosate may be linked to celiac disease and gluten intolerance. Celiac disease is associated with imbalances in gut bacteria that may be explained by the known effects of glyphosate on gut bacteria.

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