HSS 1100 Lecture Notes - Lecture 2: Cell-Mediated Immunity, Antimicrobial Resistance, Globulin

• School: University of Ottawa
• Department: Health Sciences
• Course: HSS 1100
• Professor: Franco Pagotto

Document Summary

Immunity = the protection against infectious disease conferred either by the immune response generated by immunization or previous infection or by other non-immunologic factors, aka the body"s ability to resist infection: non-specific: immunity (or natural, or innate) Acid ph: sebaceous secretions and sweat contain unsaturated fatty acids (bactericidal) Lower temperature that is suboptimal for some bacteria. Cilia of respiratory tract eliminate particles larger than 5 microns (e. g. , large bacteria-carrying dust particles). Ph - e. g. , gastric juice ph, acid ph in vagina, urine. (e. g. , transferrin, lactoferrin) that bind the iron necessary for bacterial growth. Polymorphonuclear white blood cells and monocytes as well as fixed macrophages in the tissues engulf and eventually destroy bacteria. Complement: specific immunity (or acquired, or adaptive). Mechanisms aimed at particular infecting organisms are divided into two major systems: 2. 1 specific circulating antibodies in body fluids (humoral immunity). 2. 2 cells trained to attack specific invading organisms (cell mediated immunity).