HSS 2305 Lecture Notes - Lecture 4: Mitochondrial Disease, Heteroplasmy, Inner Membrane

• School: University of Ottawa
• Department: Health Sciences
• Course: HSS 2305
• Professor: Shannon Bainbridge

Document Summary

Oxygen allows us to produce energy-> species that do this are called aerobes. Evolution from mitochondria, use oxygen to utilize atp. Many mitochondria in our cells because humans require lots of energy. Proton gradient occurs in inner membrane space. Cristae in the inner membrane, there are proteins embedded along the folds. Mitochondrial matrix; jelly like because most of it is viscous protein. Mitochondria has its own dna, not the same as in the nucleus; 13 proteins that the mito needs to function (makes it"s own proteins) Ancestry is found through your mitochondrial dna (national. Outter membrane; 50% lipids, 50% protein; allows for passage through outter membrane, have porins which allow substances to come through (permeable), can close and open. Need atp, adp to allows molecules to come in and out. Inner membrane is 75% protein, not as permeable as the outter,