HSS 2305 Lecture 29: HSS2305 Chapter 7 Part 2

• School: University of Ottawa
• Department: Health Sciences
• Course: HSS 2305
• Professor: Francois Cossette

Document Summary

These play regulatory roles in determining the shape and activities of the cells. One of the best defined extracellular matrices is basement membrane (also called: basal lamina: basement membrane, location, surrounds nerve fibers, muscles and fat cells, underlies the basal surface of epithelial tissues: Basement membranes of the capillaries play a significant role in preventing the passage of proteins out of the blood and into the tissues: In a normal kidney: the blood is filtered under high pressure, through a double-layered basement membrane that separates the capillaries of the glomerulus from the wall of the kidney tubules: connection of basement membranes to diabetes: Kidney failure in long-term diabetics may result from an abnormal thickening of the basement membranes surrounding the glomeruli: connection of basement membranes to cancers: The major components of ecm are: collagens, proteoglycans, fibronectin and laminin. Each contains binding sites for one another and for receptors on the cell surface.