HSS 2305 Lecture Notes - Lecture 13: Cancer, George Otto Gey, Henrietta Lacks

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Created the first immortal cells: cells have been used for over 74 000 research studies around the world, but bringing up ethical questions, since fam permission was never granted for scientific use of henrietta"s cells. Cancer is a genetic disease b/c it can be traced to alterations within specific genes, but in most cases it is not an inherited disease. Cancer cells become freed from many of the restraints to which normal cells are subjected due to genetic changes: normal cells do not divide unless they are stimulated to do so by homeostatic mechanisms, Do not survive if they have incurred irreparable damage, do not wander away from a tissue to start new colonies elsewhere in the body: cancer cells experience a breakdown of their regulatory influences, proliferate incontrollably, Can wander away producing malignant tumor that invade surrounding healthy tissue. Characteristics of cancer cells at cellular and genetic level.

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