HSS 3106 Lecture Notes - Lecture 3: Tylenol (Brand), Genetic Variability, Fetus

• School: University of Ottawa
• Department: Health Sciences
• Course: HSS 3106
• Professor: Ron Saulnier

Document Summary

Pharmacokinetics: describes the movement of a drug from consumption (entry) to elimination (removal). Pharmacodynamics: describes how the drug works at the target tissue. Four processes of pharmacokinetics: absorption, distribution, metabolism, excretion (some primarily excreted through urine, some through feces. It doesn"t necessarily mean they were not properly absorbed. The route of administration is determined primarily by the properties of the drug and the therapeutic objective. Oral: the most common route, by mouth (per os). While the easiest (and safest?) this pathway is the most complicated and exhibits the most variability (stomach vs. small intestine (duodenum), first pass metabolism in both the intestine and liver, gastric emptying variability, acid liability, enteric coating, etc. ) If your liver is not functioning properly, it will not metabolize the medication as fast as it should and you may be left with more medication than you need.