HSS 3106 Lecture 8: analgesic antipyretic anti-inflammatory

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Analgesics: relieve pain w/o significantly disturbing consciousness or altering actions of sensory nerves. Antipyretics: reduce fever; some also have anti-inflammatory properties. Nociceptive pain sprains, bone fractures, burns, bumps, bruises, inflammation, obstructions, myofascial pain: nociceptors are nerves which sense and respond to parts of the body which suffer from damage. Visceral pain is the subtype of nociceptive pain that involves the internal organs. It tends to be episodic and poorly localized. Semisynthetic opioids: hydrocodone - morphine derivative similar to codeine, mechanism of action surpress cough reflex by direct action on cough center in medulla, acts as. Synthetic opioid agonists competes for receptor, doesn"t rid of opioid: fentanyl (duragesic, sublimaze) analgesic and sedative used during operative and perioperative periods. Interacts with alcohol, other cns depressants, monoamine oxidase inhibitors. Instruct postoperative patients to report muscle rigidity or weakness: unusual postoperative muscle movement of the extremities, eyes, or neck, or breathing difficulties, meperidine acts on cns and organs composed of smooth muscle.

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