HSS 3305 Lecture Notes - Lecture 10: Polycystic Kidney Disease, Distal Convoluted Tubule, Renal Function

• School: University of Ottawa
• Department: Health Sciences
• Course: HSS 3305
• Professor: Karen Philips

Document Summary

Inner medulla and outer cortex: nephrons: functional units located in renal cortex, renal corpuscle: filtering unit with glomerulus and glomerular capsule, renal tubule: proximal convoluted tubule, loop of henle, distal convoluted tubule. Kidney physiology- nephron: urine production promotes homeostasis by regulating volume and composition of blood, 3 organic waste products: urea (most abundant), creatinine (produced in skeletal muscle tissue) and uric acid (formed by recycling nitrogenous base from rna molecules. Inulin is filtered but not reabsorbed or secreted, clearance is thus only function of the. 1: renin-angiotensin-aldosterone system sympathetic (ne, atrial natriuretic peptide, dopamine, prostaglandin, endothelin, nitric oxide. Urine formation: kidneys return filtered fluid to internal environment through tubular reabsorption, waste products are excreted in urine, tubular secretion removes hydrogen ions and toxins faster than through filtration. Congenital: horseshoe kid(cid:374)e(cid:455), pol(cid:455)(cid:272)(cid:455)sti(cid:272) kid(cid:374)e(cid:455) a(cid:374)d wil(cid:373)"s tu(cid:373)or. Acquired: diabetic nephropathy, glomerulo(cid:374)ephritis, kid(cid:374)e(cid:455) sto(cid:374)es, kid(cid:374)e(cid:455) tu(cid:373)ors (cid:894)wil(cid:373)"s tumor and renal cell carcinoma), pyelonephritis, renal failure (acute and chronic renal failure)