HSS 3305 Lecture Notes - Lecture 6: Thyroid, Endocrine System, Thyroiditis

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The major control systems are the nervous and endocrine systems: The nervous system is faster to respond to stress than the endocrine system. Consists of ductless glands and tissues that produce and secrete hormones. Thyroid hormone: plays an important role in controlling body metabolism. Functions of thyroid hormone: th serves to increase metabolism. o. Increase size and number of mitochondria in the cell. Increase the body"s basal metabolic rate (bmr: stimulate carbohydrate metabolism and lipolysis (break down of fats, affects protein synthesis. Etiologic factors of hypothyroidism: aging, thyroidectomy, radiation to neck/head, scleroderma, antithyroid medications, defective hormone synthesis. Goiter: visible swelling in neck, hormone synthesis tsh hyperplasia and hypertrophy of follicular cells gross enlargement, occurs in both hypothyroidism and hyperthyroidism. Signs and symptoms of hypothyroidism: s leepiness, fatigue, l oss of memory, trouble concentrating, u nusually dry skin, g oiter, g radual personality change, depression. I ncrease in weight: s ensitivity to cold, h air loss.

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