APA 2312 Lecture 3: Muscle Physiology 1

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Muscle is a biological machine: muscle converts chemical energy stored in atp to mechanical work and heat. The muscular system functions to: produce body movement (locomotion, stabilize body position (posture, store and move substances, glycogen, cardiovascular and respiratory muscles help to move nutrients & oxygen, produce body heat, thermoregulation. Muscle types: skeletal muscle, smooth muscle, cardiac muscle. Basic features of a skeletal muscle: muscle attachments. Most skeletal muscles run from one bone to another. One bone will move other bone remains fixed: origin less movable attachment, insertion more movable attachment. Connective tissue: epimysium: surrounds entire muscle, perimysium: divides muscle into sections called fascicles, endomysium: surrounds individual muscle fibres, tendon: attaches muscle to bone. Nucleus: stores genetic material for cell division and production of protein. Are bundles of contractile protein = myofilaments. 2 types of myofilament: actin filaments, myosin filaments. Myofibrils are anchored to the inner surface of the sarcolemma. A single t-tubule and the 2 terminal cisternae form a triad.

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