MIC 4100 Lecture Notes - Lecture 1: Gram Staining, Humoral Immunity, Antimicrobial Resistance

• School: University of Ottawa
• Department: Microbiology and Immunology
• Course: MIC 4100
• Professor: Franco Pagotto

Document Summary

Eukaryotes- they have a nucleus, membrane, etc. Resident (stay with you for life) vs. transient (come and go-surgery, overdoing it with antibiotics) flora. Immunity: non-specific (innate): things that are already there, we are born with it, specific (adaptive): A physical barrier, its dry and acidic- bacteria need water. Iron-binding proteins- prevents iron from being available to the microorganism. Complement: a set of circulating proteins in the blood. Complement proteins are able to recognize surface sugars, they can come together and form a (cid:498)pore(cid:499) mac, Adaptive: specific against one type of invader; depicted usually on past exposure and this causes the bacteria to leak out. T helper 2 cells: bind to b cells and tell them to start making antibodies. Antibodies: protein that binds specifically to a substance. Recognize toxins, etc: constant region= allows immune system to recognize what is bound to it, variable region= responsible for antigen recognition. Primary immune response: the first time you encounter an antigen.