PHS 4300 Lecture Notes - Lecture 6: Amyotrophic Lateral Sclerosis, Cerebral Palsy, Dorsal Root Ganglion

• School: University of Ottawa
• Department: Physiology
• Course: PHS 4300
• Professor: Joanne Savory

Document Summary

Neuron anatomy: cell, dendrites, axon: neural network = synaptic contact btwn axon to dendrites. White matter where axons are tightly packed (colour from myelin sheaths); 100x faster than w/o myelin: nerve pns; tract/column cord. Grey matter where cell bodies (somas) are found; uncommon but mostly for pain: found as a nuclei (somas crowded together like red nucleus) or as a cortex (web-like arrangement like. A reflex arc is the simplest connection, using only 3 neurons (sensory to interneuron/association to motor) More complicated functions (perception/movements) requires several million of the 10-50 billion in the ns but same principle as simple reflex applies. Immune system: myasthenia gravis antibodies attack ach receptors on skeletal muscle, degeneration (e. g. alzheimer"s half of cortical neurons are lost) Most common are migraine, stroke, alzheimer"s disease, traumatic brain or spinal cord injury, epilepsy, autism, parkinson"s disease, tourette"s syndrome, ms, cerebral palsy and amyotrophic lateral sclerosis: all treatment revolves around returning the brain to normal pre-injury" conditions.