PHS 4300 Lecture Notes - Lecture 1: World Health Organization, Iron-Deficiency Anemia, Psoriasis

• School: University of Ottawa
• Department: Physiology
• Course: PHS 4300
• Professor: Frank Feiner

Document Summary

Hypoxia stimulating the kidneys to release erythropoietin to stimulate rbc growth: kidneys sense hypoxia in bloodstream = release erythropoietin stimulating the bone marrow, synthesizes rbcs from erythroid precursor cells. Protein, iron, vitamin b12, folic acid necessary substances for healthy rbc production. Blood types: su(cid:396)fa(cid:272)e a(cid:374)tige(cid:374)s o(cid:374) all (cid:271)od(cid:455) (cid:272)ells a(cid:374)d bc(cid:859)s, spe(cid:272)ifi(cid:272) a(cid:374)tige(cid:374)s o(cid:374) bc(cid:859)s a(cid:396)e aggluti(cid:374)oge(cid:374)s, type a and type b, abo blood type classification system categorizes blood into four types, a, b, ab and o. If rbc surface has rh factor, categorized as positive. If rbc surface does not have rh factor, categorized as negative: rh factor another antigen on rbcs (d antigen, all blood types are either rh- or rh+ If rh- comes into contact with rh+; 80% of the time rh- individual with develop anti-d antibodies. Rbc pathophysiology: defined as a decreased rbc mass that becomes clinically apparent when levels of hb and.