PSY 3391 Lecture Notes - Lecture 16: Amygdala, Ketone Bodies, Optic Chiasm

• School: University of Ottawa
• Department: Psychology
• Course: PSY 3391
• Professor: Nafissa Ismail

Document Summary

Table 9. 3 signaling molecules involved in regulation of energy balance. When we eat: amount of glucose in system (pancreas) Inhibit leptin because we require glucose (satiety: orexigenic increases with food intake, red blood cells, produces lactate which is converted into glucose (liver) Inject insulin: external pancreas, usually develops slowly in adults, tissues develop an insensitivity to insulin, leading to increased insulin secretion, either due to pancreas receptors, cannot receive them, either down regulates, morphological change, linked with obesity. Gonadal steroid hormones, food intake and body mass. Estrogens and progestins: ovariectomy increases food intake and increases body weight by about 20-25% in female rats, the hyperphagia will eventually wane, and food intake will stabilize to maintain this new elevated body mass. The effects of ovariectomy and progesterone treatment are virtually identical, but nonadditive. Estrous cycling: since steroid hormones have these dynamic effects on food intake and body weight, there should be changes during estrous cycling, pregnancy, and pseudopregnancy.