PSY 4327 Lecture Notes - Lecture 5: Tryptophan, Lorazepam, Hypersomnia

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Sleep and infections: good for what ails you. Increase in sleepiness: n3 and delta waves increase, rem decreases during infection (e. g. , fevers, timing of sleep via circadian rhythm not affected, sleep-specific; not circadian. Increased sleep helps recovery and helps prevent contagion: sleep deprivation lowers immune response- even one night of it, feedback from the immune system, hiv+ who develop aids have daytime sleepiness, night insomnia, less n3. In final stages lethargy, daytime sleepiness, no rem/nrem cycle, n3 almost gone: sleep disturbances predict prognosis. Hypothalamo-pituitary-adrenal (hpa) system (e. g. , cortisol) are suppressed: this effect is exactly the opposite of the effects of stress. Pain/strong stimuli: vicious cycle with pain, acute or chronic pain both, reduce sws. Exercise: exercising 4-8 hours before bedtime is beneficial to sleep if core temperature goes up. Increases sws: slightly delays rem onset, slightly reduced rems (likely due to temperature)

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