BIO152H5 Lecture Notes - Lecture 14: Genetic Variation, Phenotype, Gene Flow

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16 Aug 2020
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Microevolution is a change in allele frequencies in a population over generations. Genetic variation among individuals is caused by differences in genes or other dna segments. Phenotype is the product of inherited genotype and environmental influences. Natural selection can only act on variation with a genetic component. Genetic variation can be measured as gene variability or nucleotide variability. Average heterozygosity measures the average percent of loci that are heterozygous in population. Nucleotide variability is measured by comparing dna sequences of pairs of individuals . Some phenotypic variation does not result from genetic differences, but rather from environmental influences. For example, caterpillars can have different appearances due to chemicals in diet, not their genotype. Only genetically determined variation can have evolutionary consequences. A mutation is a random change in nucleotide sequence of dna. A point mutation is a change in one base in a gene. Only mutation in cells that produce gametes can be passed to offspring.

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