BIO152H5 Lecture Notes - Lecture 15: Outcrossing, Semen Analysis, Acinonyx

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28 Dec 2014
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2. variety of species: genetic diversity within species. Genetic considerations: small population size, inbreeding, demographic considerations, immigration/emigration, connectivity: gene flow. Loss of genetic diversity: population bottlenecks, founder effects, genetic drift. Genetic consequences of small population size: inbreeding, inbreeding depression, fixation of deleterious genes. Decline in average fitness in a population that takes place when . increases. Can increase the rate at which natural selection exposes disadvantageous recessive alleles in the homozygous phenotype. 2 processes: many recessive alleles represent loss of function mutations, many genes involved in fighting disease have a heterozygote advantage. Cheetah (acinonyx jubatus: restricted to two wild populations in southern & eastern africa, a survey of 52 proteins indicated complete monomorpism (had 1 form of each protein). Other cats have 8-21% of loci polymorphic: variability at the mhc (major histocompatability complex: genetic locus in mammals that directs synthesis of antigens on the surface of most cells)

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