BIO206H5 Lecture Notes - Lecture 3: Turbidity, Photodetector, Absorbance

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Bio206 lecture 3 nucleotide bases always face inwards. B-dna has grooves alternating with minor and major grooves angle between carbon and base is 51. 5 degrees. Major groove plays major role in gene regulation proteins and amino acids interact with the edges of the major grooves binds with net electrical charge of dna. Dna has histones that have a net positive charge. Dna is regular and symmetrical with few chemical groups exposed for further. Lacks oh group on 2"c of the sugar: more stable than rna and highly resistant. Orderliness and stability dependable information carrier (and no evidence of reactions to degradation catalytic activity) All c"1 are pointed towards the centre of the dna molecule. Base are attached to that particular sugar therefore all bases point inwards as well. Rna: native form is a single stranded molecule. Intramolecular base pairing hydrogen bonding with complementary base pairs: Rna is only single stranded however it can fold back on itself and bond intramolecularly.