BIO304H5 Lecture Notes - Lecture 9: Patch Clamp, Membrane Potential, Pipette
Document Summary
Its through ap and synapses that information is carried through our body. For sodium, we are approaching a point where there is 0 energy for current flow and then its reversing. For potassium, every step we take, incrementally increasing the energy for potassium flow while increasing the amount of channels opening for potassium: this is why the potassium current only gets bigger. Slide 7: the potassium channels are less responsive. If i depolarize, the sodium conductance rises and then shuts off. Slide 8: we are looking at how the voltage changes during an ap. Slide 10: they could then determine at the new voltage and conductance what the current is, we have new values of current. Slide 19: patch clamp, permits the recording of single channel currents. Slide 21: when there is a depolarization in the membrane, the pore loops come out of the membrane opening up a pathway.
