BIO304H5 Lecture Notes - Lecture 14: Nicotinic Acetylcholine Receptor, Exocytosis, Electron Microscope
Document Summary
Slide 5: one of the great purposes of an ap is to reach nerve terminals where we have these specialized arrangements where these neurons communicate with other cells, the vesicles are loaded with ntrs. It is through that calcium influx that occurred from the ap that synaptic vesicles fuse with the membrane. Slide 8: there were some key inconsistencies in the experiments that suggested it might not only be electrical signals. Information moves in a unidirectional manner: people started noticing that synapses could be either excitatory or inhibitory. How is it that i can excite this neuron and in some cases the postsynaptic neuron becomes excited and other cases it becomes inhibited. How can you excite one neuron which is an excitatory electrical signal that is transmitted electronically that should also be excitatory on a postsynaptic cell. Slide 11: chemical synapses can occur between various types of cells, glial cells, supportive cells.
