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Lecture 6

PSY333 - Lecture 6.docx

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University of Toronto Mississauga
Gordon Anderson

Lecture 6 Chapters 3-5 The Cardiovascular Stress Response Step 2 - endothelial cells help to pump blood - secrete nitric oxide which helps to secrete blood The Cardiovascular Stress Response Step 3 - Water helps blood to remain viscous - Body re-absorbs water via vasopressin (anti-diuretic) - On diuretic, makes you pee all the time - Athletes – you need water, WHY? o Water helps to get oxygen, nutrients to muscles - Why pee your pants if you are really stressed? o Dead weight o Because bladder is uni-directional  Nothing can go back  Can only go one way out The Cardiovascular Stress Response Recovery - shutting down the stress-response system Chronic Stress and Cardio Disease - can lead to cardiovascular disease over time - What is high BP? o 140/90 - Why is blood pressure going up? o Obesity/lack of exercise - Step 2 o Vulnerable part of a capillary  The intersections between them  They are branches • Risky part because anytime you have a branch have a thinner spot, and have huge amount of blood pressure pumping in trying to split off o Putting a lot of pressure on it o Very difficult to control  As hypertension goes on, those vessels become more resistant • Increases blood pressure even more o Become hardened  Vascular resistance – don’t open and shut flexibly - Step 3 o Left ventricular hypertrophy  Lop-sided part • Results in irregular heartbeat o Super strong predictor of cardiovascular disease o Bifurcation – where capillaries meet o As hypertension continues, pits and tears along artery walls - Step 4 o Pits and tears can happen on the outside of the vessel  As well as the endothelial cells o CRP Lecture 6  Indicator of inflammation  C-reactive protein o SNS = viscous blood  For what purpose? • Blood becomes easier to clot o If you get injured, don’t bleed out  But makes it harder to pump blood o Claudication  Oxygen depletion to one area • Can cause area to die – nacradic heart? o Thrombus  When plaque breaks off, sticks somewhere, and causes blockage • Can travel to blood vessel • Brain - stroke • Somewhere in your body – heart attack Social Dominance and Cardio Disease - What happens if social hierarchy is unstable? o High rank monkeys go through more cardio disease risk factors?  Because they have to keep fighting for their top spot o Lower rank stay the same  Never had the top spot in the first place Hypertension and the Brain - neurocognitive decline as middle age - Children and cognition o Surge of type II diabetes  Hypertension is on the rise in children • Those kids performed less well on tests in school/home with memory, everything o Not just a matter of aging  If you have hypertension anytime in your life, going to relate t
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