PSY395H5 Lecture Notes - Lecture 2: Pregnenolone, Second Messenger System, Hydrophile
Document Summary
Chemical signaling: intracrine mediation: communication within the cell that regulates intracellular events. In these cells, there are speci c binding sites (hormone receptors): etocrine mediation: this type of mediation is related to substances such as pheromones, that are released into the environment by individuals to communicate with others. Cells as hormone targets: the action of hormones in the cells is basically protein modi cation and regulation, gene regulation by hormones can happen in two ways: transcriptional or post- translational. The transcriptional regulation affects the amount of mrna and its synthesis, causing effects on transcription. This type of regulation has slow onset and offset and causes long-term changes. Some hormone receptors are transcription factors that affect directly mrna synthesis. This type of regulation has fast onset and offset. Transcription factor receptors: the ve major classes of steroid hormone receptors belong to this category.
