BIOB51H3 Lecture 7: Lecture 7 note
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Genetic variation differences in phenotype due to differences in genotype: 2. Environmental variation differences in phenotype due to differences in genotype: 3. Genotype x environment differences in phenotype due to differences in the effect of external conditions on individuals with different genotypes: genetic variation in types of encoded proteins; amount, timing, or location of expression, ex. Humans tas2r38 gene, affects bitterness in food: avi/pav have 2 avi alleles, you eat more vegetables but if you have 2. It can, if based on genotypes: environmental variation. Yes: genotype can become more prevalent, some disappear. Damage or chemical alteration of dna: 3. Lack of repair (e. g. by dna polymerase: eg. sickle-cell anemia (single base pair substitution in hemoglobin gene, eg. Indels insertions or deletions of nucleotides in dna sequence: higher frequency in introns than exons (non-expressed dna because of selection, can shift codon reading frame, changes the meaning of all downstream codons. Indels can build up more in introns: indel causes, 1.
