BIOC13H3 Lecture Notes - Lecture 11: Rotenone, Flavoprotein, Succinic Acid
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3 copies of complex iii and 6 of complex iv. Complex iii (ubh2-cyt c oxidoreductase: lets us know the electrons enter complex iii by ubiquinol and the electrons pass through complex iii and are donated to cytochrome c, move electrons from one mobile carrier, q, to cytochrome c. Complex iv (cytochrome c oxidase: electrons go from cytochrome c to oxygen, the terminal electron acceptor. K (lysine: the reduction potentials of the centers are isopotential until electrons are passed to oxygen, which is where there is a large release of energy, presumably this occurs at the bimetallic centre. Complex iv inhibitors: cyanide, binds to heme a3 only (complexes with it, causes its reduction potential to become more negative, can"t accept electrons from heme a, electron transport gets shut down, proton pumping can"t occur. Aox inefficient pathway: given ammonium as nitrate source, there is a huge increase in the expression of. If fungus is sensitive to cyanide in its.
