BIOC14H3 Lecture Notes - Lecture 6: Genetically Modified Organism, Knockin, Transgene
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Slide 2: genome management, how do we modify organisms and the techniques. Slide 3: when we have these organisms, we can either control the genetics of the environment, the big questions are how relevant are the finding to the natural condition. Esp if they a(cid:396)e ge(cid:374)eti(cid:272)all(cid:455) (cid:373)odified, the(cid:455) a(cid:396)e (cid:373)o(cid:396)e e(cid:454)pe(cid:374)si(cid:448)e : higher organisms, they would be more and more expensive, so depends on what we are going to work with and the strains. O(cid:396) if the(cid:455) (cid:374)eed to (cid:271)e take(cid:374) care around the clock in genetically modified o(cid:396)ga(cid:374)is(cid:373)s What are the tools (cid:449)e (cid:272)a(cid:374) use to do a (cid:272)e(cid:396)tai(cid:374) ge(cid:374)eti(cid:272) (cid:373)odifi(cid:272)atio(cid:374) . If so(cid:373)ethi(cid:374)g is (cid:449)(cid:396)o(cid:374)g (cid:449)ith ge(cid:374)es, the(cid:374) (cid:449)e ha(cid:448)e a broken machine (so something will go wrong) If (cid:449)e ha(cid:448)e o(cid:374)e gea(cid:396) i(cid:374) that (cid:373)a(cid:272)hi(cid:374)e, so it is (cid:271)a(cid:396)el(cid:455) fu(cid:374)(cid:272)tio(cid:374)i(cid:374)g . This is (cid:396)elated to ge(cid:374)e fu(cid:374)(cid:272)tio(cid:374) si(cid:374)(cid:272)e the(cid:396)e is so(cid:373)e (cid:373)utatio(cid:374) i(cid:374) ge(cid:374)e fu(cid:374)(cid:272)tio(cid:374) that is (cid:374)ot fu(cid:374)(cid:272)tio(cid:374)i(cid:374)g p(cid:396)ope(cid:396)l(cid:455) .
