BIOC14H3 Lecture Notes - Lecture 11: Monoamine Oxidase A, Monoamine Oxidase, Major Depressive Episode
Document Summary
Prevalence: depression, monoamine hypothesis of depression, mouse models, neurogenesis, anxiety, diagnostic criteria. Ssri and anxiety: neurogenesis, genetic influences, video: epigenetics: the ghost in your genes (~40 min) Characterized by persistent abnormalities of emotional state can disrupt normal daily activities: major depression. Chronic feelings of sadness, apathy, worthlessness, despair, helplessness, lethargy, lack of sexual drive, insomnia and in extreme cases, suicidal tendencies. Bipolar disorder (type i and ii: alternating feelings of depression (days-weeks) and mania (relatively shorter duration, depressive episodes followed by abnormally elevated physical and mental. Type ii is milder form of type i. Chronic state of mild depression symptoms not as severe as depression but patients are at high risk of undergoing major depressive episodes. Similar to bipolar disorder with ups and downs in the patients" mood but not as extreme tends not to affect day-to-day life but patients are at a higher risk of developing bipolar disorder.
