BIOC19H3 Lecture 7: Notes
Document Summary
Skeletal muscle: comprised of elongated, multinucleated cells called muscle fiber cells packed full of muscle specific proteins organized into myofilaments, myofilaments are contractile units of muscles, skeletal muscles are involved in voluntary muscle movement. Inside the muscle you have bundles of cells they are labelled as muscle fiber cells. Within each muscle fiber cells you have contractile units myofilament and actin. The bundles of muscle fiber cells are called fascicle: from the mesoderm is where the skeletal muscles develop. Mesoderm division: after gastrulation the mesoderm is divided into 3 regions, a bulk of mesoderm cells that buds off is the lateral plate mesoderm. It forms body wall, gut wall, circulatory system and cartilage of limbs: the intermediate mesoderm gives rise to kidney and gonads, paraxial mesoderm gives rise to somite (gives rise to skeletal muscles). Division into individual somites, start at head and move down to tail: axial mesoderm forms notochord (first backbone), under neural tube.