BIOC33H3 Lecture Notes - Lecture 19: Umbilical Artery, Fetal Hemoglobin, Partial Pressure
23 Mar 2016
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Human physiology 2 respiratory physiology: pulmonary venilaion. Hemoglobin can exist in 2 diferent states t-state (tense) or r-state (relaxed: t-state. 100 po2 (torr), arterial pressure is only 20% saturated in this form: r-state. Has a much greater ainity for o2. 40 po2 (torr), venous pressure, molecule would be 90% saturated even under these condiions: hemoglobin can alternate between these 2 forms as the result of binding and unbinding of. O2: overall curve between hemoglobin saturaion and po2 is just a hybrid of the t-state and r- State curve: there is a slow iniially binding of o2 to the hemoglobin iniially in the t-state, once o2 binds to it facilitates transiion to the r-state get a large rise in hemoglobin ainity. Then it levels of once you get to the high levels of o2. (provides a safety margin against expose to high alitudes, lung disorders, etc.
