BIOC34H3 Lecture Notes - Lecture 9: Angiotensin-Converting Enzyme, Baroreflex, Posterior Pituitary
Document Summary
Lecture 9 blood pressure (cont. ) and lung mechanics i. Blood pressure regulation: baroreceptor activity, baroreceptors send ap to the brain. Increased bp vessels stretch ion channels open depolarization of baroreceptors . Resets the pressure baseline for baroreceptors desensitizes them. If it did return back to the original normal levels stimulus that caused baroreflex would cause bp to drop again. Location of adrenoceptors: a- sympathetic nerve terminal endings; b- diffusely scattered around vessels. Increase in blood osmolarity act on osmoreceptors triggers adh release vasoconstriction increase tpr, bp promote water retention in kidney increase bp and blood volume: angiotensin. When bp is decreased or there is a presence of osmotic/ionic disruptions cells in kidney release. Renin cleaves off angiotensinogen produced angiotensin i. A1 a2(angiotension 2) via ace (angiotensin converting enzyme) Ace is present in the lungs; lines capillaries in the lungs so as blood flows thru the lungs, this reaction can take place. A2 tremendous ability for vasoconstriction to take place.
