BIOB10H3 Lecture Notes - Osteoclast, Leading Edge, Phagolysosome
6 Dec 2012
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Document Summary
Cytosolic proteins don t have a transfer sequence since they just stay in the cytoplasm. The targeting sequence for proteins destined to stay in the cytosol is nothing; there is no targeting sequence for these proteins. The cytoskeleton is made up of 3 components: microtubules, actin, intermediate filaments. The function of the cytoskeleton is for: dynamic scaffold structure and support, spatial positioning of organelles, intracellular transport, cell contraction/cell motility/phagocytosis, machinery for cell division. Figure 9. 1 an overview of the structure and functions of the cytoskeleton. Scehmatic drawings of (a) an epithelial cell, (b) a nerve cell, and (c) a dividing cell. The microtubules of the epithelial and nerve cells function primarily in support and organelle transport, whereas the microtubules of the dividing cell form the mitotic spindle required for chromosome segregation. Intermediate filaments provide structural support for both the epithelial cell and nerve cell.
