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BIOC51H3 (51)
Lecture 13

BGYB51H3 Lecture 13 Notes Oct 22

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Department
Biological Sciences
Course
BIOC51H3
Professor
Maydianne Andrade
Semester
Fall

Description
BGYB51H3 Lecture 13 Notes -HIV is a retrovirus that carries reverse transcriptase to convert RNA to DNA and carries integrase to integrate DNA and protease -GP120 is the surface protein that binds to the membrane -CD4 protein and co-receptor bind with GP120 protein of HIV -in reverse transcription of HIV, DNA is created from RNA -HIV evolution involves selection inside the body of the host and selection across the population of the host -HIV infects helper T cells that recognize foreign proteins, activate killer T cells and signals antibody production -AZT is a treatment of HIV in which it ends reverse transcription -HIV evolves resistance to AZT because of mutant forms of HIV reverse transcriptase arising -mutations can cause
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