EESA01H3 Lecture Notes - Lecture 4: Ddt, Bisphenol A, Carcinogen
3 Mar 2018
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This is called mimicking: very hard to study and most data comes from animal studies and is not always reliable, hormones are called endocrine disruptors. This because of two major effects: direct effects and indirect effects: direct effects: the chemical can bind to hormone receptor, alter the appearance of some genes, and changes the level of produced protein. Indirect effects: this one is all about changing hormones. Includes altering hormone production, transport and metabolism: fetuses are much more sensitive than adults. Health implications of endocrine disrupters: feminization of males: roosters began acting different than normal. Frogs that were male became completely fertile females under the exposure to ddt: abnormal sexual behaviour, birth defects, altered time to puberty. !1: cancer of mammary glands or testes, thyroid dysfunction: strong implication on infants. Thursday, february 22, 2018: tsh is thyroid stimulatory hormone and stimulates t3 and tf. Case study: pesticides and children: study compared two groups of preschoolers in mexico.
