EESA10H3 Lecture Notes - Electron Microscope, Hemoglobin, Encephalitis

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18 Apr 2012
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-influenza is a disease that had killed before
-we are defenseless and we don’t have a vaccine that will provide long-
term immunity against influenza
-most infections are worldwide
-influenza virus are replicating life forms and they have no purpose
other than to replicate and so we have to consider not only the end
result of the replication but also the biology that goes into the
replication to really understand these agents and use that knowledge so
we can replicate better than they do
-victims number in the thousands due to influenza
-since 1957, 700,000-750,000 individuals have died during the non-
pandemic seasons in the United States
-during a minor epidemic in France, 30,000 people may die from the flu
in three short weeks that’s twice as many that have died of AIDS in
ten years
-the modern history of the flu began in London, England
-in 1927, ferrets were used to research the influenza virus
-in 1933, Christopher Andrews and his colleagues were able to isolate
the first human influenza virus from a ferret which caught the flu from
one of the lab assistants
-from 1933 on, ferrets have been coming down with the human flu
-with the invention of the electron microscope, more was found out
about the virus learned how it infects cells and its size (more than a
million virus can condense on a pin –usually the flu comes on very
quickly, starts off with a high fever and affects the whole body, get
aching muscles, headaches, a dry cough and a high fever
-with a cold the symptoms are more localized, a stuffy nose, a sore
throat, no/mild fever
-flu is an airborne virus that multiplies in the respiratory tract and it is
transmitted by tiny droplets in the air like the spray of an aerosol can
-the moment an infect cough/sneezes, the person nearby becomes
infected by the virus the droplets are microscopic
-the virus can be transferred by inanimate objects the virus can
survive up to an hour on inanimate surfaces why washing hands
frequently is important
-there are three types of influenza viruses Type A, B, and C
-Type A is the most dangerous has subtypes and surface protein
(hemoglobin and neuroaminidase) are used to distinguish between them
H and N
-starting with H1N1, every member of the extended family has its
own nickname
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