EESA10H3 Lecture Notes - Transgene, Benzene, Glyphosate
15 Sep 2013
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Screening level risk assessment for a 70 kg male who has worked as an auto mechanic for 8 hours per day for 25 years. The chemical of concern is benzene that has been proven carcinogen and is a constituent of gasoline and automobile exhaust gases. The estimated daily intake (edi) is calculated below for two routes of exposure, through air, as in inhalation and breathing and through absorption, from the grease on hands. The medium the receptor receive his greatest exposure is from inhalation. This could be because a person breathes at a much faster rate than the rate of absorption by skin. It is unlikely for the person to have grease on their hands all the time. Hence, benzene is presented in the air at all times, so the workers may be exposed to it even if he is just relaxing, eating, etc. The calculations for relative margin of safety (rmos) are show below:
