HLTB16H3 Lecture Notes - Lecture 14: Glycated Hemoglobin, Blood Sugar, Atherosclerosis

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Disease burden, accounts for 22% of deaths in females (women see docs more), 26% in males. bil in mortality costs, physician/hospital services, lost productivity. 80% of canadians have @ least 1 risk factor for cvd: physiological mechanisms, atherosclerosis contributes to cvd, causes heart attacks & strokes, risk factors: high cholesterol, diabetes, smoking, excess alcohol. Plaque narrows arteries, restricts blood flow, clot formation consumption, etc. Undiagnosed diabetes: canadian study found 1. 13% of canadian adult pop (20+) had undiagnosed diabetes based on fasting plasma glucose levels, hemoglobin a1c test demonstrates average level of blood sugar, canadian guidelines diagnosis criteria: hemoglobin a1c level of >/ 2/5 canadians will develop cancer in their lifetime (40% of women & 206,200 new cases of cancer & 80,800 deaths from cancer in canada. 1/2 all new ages will be lung, colorectal, breast & prostate cancers in 2017. *if treatment effectiveness not proven, then not unethical to not give any to control group.

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